Derived Datasets
Access to all files tagged as "controlled" is login-secured. These controlled dataset used in this publication are accessible to the research community as described under private data download guidleine
FunSeq ouput
FunSeq output for PCAWG mutations using PCAWG-specific data context(link to Synapse):
ALoFT ouput
ALoFt output for putative loss-of-function mutations in PCAWG (link to Synapse):
TF motif gain or loss enrichment files
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P-value associated with gain-of-motif events in PCAWG (uniform background):
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P-value associated with loss-of-motif events in PCAWG (uniform background):
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P-value associated with gain-of-motif events in PCAWG (signature-corrected background):
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P-value associated with loss-of-motif events in PCAWG (signature-corrected background):
Weak Drivers in PCAWG
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List of weak driver elements in PCAWG:
Randomized PCAWG mutations
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Simulated mutations (moatsim randomization):
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Simulated mutations (broad randomization):
VAF-based heterogeneity scores
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Coding mutations:
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nonCoding mutations:
Signature Differences
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SigProfiler based signature output:
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SigAnalyzer based signature output: